Oesophageal lesions during treatment with piroxicam.

Case report: treatment of migraines with compounded piroxicam mini-troches.

WHAT CAUSES A MIGRAINE? A migraine is caused by abnormal brain activity, although the exact chain of events remains unknown. One common theory is that a drop in serotonin levels causes blood vessels to swell, leading to migraine pain and associated symptoms. Some people have a warning symptom or set of symptoms preceding the onset of the headache, which is referred to as an aura. Others have no...

Oesophageal tuberculosis mimicking a tumour during treatment for nodal tuberculosis.

A patient with cervical lymph node tuberculosis developed a tubercular ulcer in the oesophagus eight weeks after starting treatment. This was probably due to a drug related hypersensitivity reaction in an adjacent mediastinal lymph node and subsided with continued treatment.

Treatment of oesophageal perforation.

Piroxicam-β-Cyclodextrin: A GI Safer Piroxicam

Although NSAIDs are very effective drugs, their use is associated with a broad spectrum of adverse reactions in the liver, kidney, cardiovascular (CV) system, skin and gut. Gastrointestinal (GI) side effects are the most common and constitute a wide clinical spectrum ranging from dyspepsia, heartburn and abdominal discomfort to more serious events such as peptic ulcer with life-threatening comp...

OESOPHAGUS Relevance of ineffective oesophageal motility during oesophageal acid clearance

Background: Oesophageal clearance of acid reflux consists of an initial volume clearance followed by neutralisation of the acidified mucosa by swallowed saliva (chemical clearance). Ineffective oesophageal motility (IOM), a frequent finding in patients with gastro-oesophageal reflux disease (GORD), has been claimed to underlie prolonged acid clearance by affecting oesophageal emptying and saliv...